India Bohanna - Experimental Neuropsychology Research Unit

New therapies are being developed for the treatment of Huntington's disease,
an inherited neurodegenerative disease characterised by the gradual onset of
motor, cognitive and psychiatric symptoms. These new treatments provide some
hope that in the not too distant future, the onset of symptoms in people who
have the HD gene may be delayed and/or the progression of disease slowed.
However, in order to efficiently test these new therapies for their ability
to delay or slow disease, it is imperative that non-invasive and
symptom-independent biomarkers of early neuropathological change are
identified. My research is focused on using Magnetic Resonance Imaging
(MRI), diffusion tensor imaging (DTI) and functional MRI (fMRI) to identify
potential markers of disease onset and progression during the
pre-symptomatic and early symptomatic stage of HD.