Dr David Reser
Phone:+61 3 990 51210
ORCID identifier: http://orcid.org/0000-0002-5130-1255
I completed my Ph.D. in the Behavioural and Systems Neuroscience Group at the Albert Einstein College of Medicine in New York, USA, and subsequently worked as a Postdoctoral Fellow in the Laboratory for Integrative and Cognitive Neuroscience at Georgetown University. In both laboratories, I was involved in studies of the functional organisation of auditory areas in the cerebral cortex, and their role in processing complex sounds such as speech and music.
I am currently a member of the research group led by Professor Marcello Rosa, where I am involved with investigations of the anatomy and physiology of auditory-visual interactions in the brain. Of particular interest is the role of the limbic system, which processes emotions, in the perception of temporally and spectrally complex sounds.
Our efforts to map connections of the cerebral cortex have led to an examination of the claustrum, an evolutionarily old, but still poorly understood region of the mammalian brain, which has been implicated in integration of signals from multiple sensory and limbic brain areas. The claustrum may be involved in generating a coherent sensory image of the world, and may contribute to maintenance or alteration of states of awareness. Interest in this enigmatic structure has been reinvigorated by controversial suggestions that the claustrum may play a role in consciousness itself. We are now attempting to shed light on the function of the claustrum through a detailed examination of its anatomy and connections with other brain areas.
I am also involved in a series of experiments looking at the neurophysiology of colour vision in the brain of the honeybee. This is part of a collaboration with Dr Adrian Dyer, in which we hope to understand how the relatively simple (at least compared to vertebrates) bee brain is capable of producing a remarkable range of complex behaviours, including higher-order decision making and experience-dependent changes in cognitive strategy.
Inquiries from students interested in pursuing independent study or Honours/HDR projects related to the above research topics are always welcome.
Primary Chief Investigator, NHMRC Discovery Project Grant 1068140: "The claustrum enigma: unlocking the role of the last unknown area of the primate brain". Funding approved for 2014-2016.
http://www.peerJ.com- Open access, peer reviewed Biology research
http://www.f1000.com- Expert reviews and commentary on current literature
David H. Reser, Piotr Majka, Shakira Snell, Jonathan Chan, Kirsty Watkins, Katrina Worthy, Maria Del Mar Quiroga, Marcello G.P. Rosa (in press) Topography of claustrum and insula projections to medial prefrontal and anterior cingulate cortex of the common marmoset (Callithrix jacchus). Journal of Comparative Neurology.
Cristina M. Patru and David H. Reser (2015) A new perspective on delusional states: Evidence for claustrum involvement. Frontiers in Psychiatry 6:158. doi: 10.3389/fpsyt.2015.00158.
Leo L. Lui, Yasamin Mokri, David H. Reser, Marcello G.P. Rosa, and Ramesh Rajan. (2015) Responses of neurons in the marmoset primary auditory cortex to interaural level differences: comparison of pure tones and vocalizations. Frontiers in Neuroscience. 9:132. doi: 10.3389/fnins.2015.00132
Burman KJ, Bakola S, Richardson KE, Yu H, Reser DH, Rosa MG. (2014). Cortical and thalamic projections to cytoarchitectural areas 6Va and 8C of the marmoset monkey: connectionally distinct subdivisions of the lateral premotor cortex. Journal of Comparative Neurology. doi: 10.1002/cne.23734
Reser DH, Richardson KE, Montibeller Md, Zhao S, Chan JM, Soares JG, Chaplin TA, Gattass R and Rosa M (2014). Claustrum projections to prefrontal cortex in the capuchin monkey, Cebus apella. Frontiers in Systems Neuroscience. 8:123. DOI: 10.3389/fnsys.2014.00123
Burman, K. J., Bakola, S., Richardson, K. E., Reser, D. H. and Rosa, M. G.P. (2014), Patterns of afferent input to the caudal and rostral areas of the dorsal premotor cortex (6DC and 6DR) in the marmoset monkey. Journal of Comparative Neurology. DOI: 10.1002/cne.23633
Reser, David H., and Rosa, Marcello G.P. Perceptual elements in brain mechanisms of acoustic communication in humans and nonhuman primates. Behavioral and Brain Sciences 37(6):571-2. doi: 10.1017/S0140525X13004196..
Bosco, Annalisa; Breveglieri, Rossella; Reser, David; Galletti, Claudio; Fattori, Patrizia. Multiple representations of reaching space in the medial posterior parietal area V6A. Cerebral Cortex Advance Access online 12/1 2014. DOI: 10.1093/cercor/bht420
Burman, Kathleen; Bakola, Sophia; Richardson, Karyn; Reser, David; Rosa, Marcello. Patterns of cortical input to the primary motor area in the marmoset monkey. Journal of Comparative Neurology. (Advance publication DOI: 10.1002/cne.23447).
Hsin-Hao Yu, Tristan Chaplin, Gregory Egan, David Reser, Katrina Worthy, and Marcello Rosa. Visually-evoked responses in extrastriate area MT following lesions of striate cortex in early life. Journal of Neuroscience 33(30):12479-12489 (2013).
Collette Mann, Benedict Canny, David Reser, and Ramesh Rajan. Poorer verbal working memory for a second language selectively impacts academic achievement in university medical students. PeerJ 1:e22 http://dx.doi.org/10.7717/peerj.22 (2013).
Ramesh Rajan, Vladimir Dubaj, David Reser, and Marcello G.P. Rosa. Auditory cortex of the marmoset monkey: Complex responses to tones and vocalisations under opiate anaesthesia in core and belt areas. European Journal of Neuroscience 37(6):924-41. DOI: 10.1111/ejn.12092 (2013).
Reser DH, Burman KJ, Yu HH, Chaplin TA, Richardson KE, Worthy KH, Rosa MG. Contrasting patterns of cortical input to architectural subdivisions of the area 8 complex: A retrograde tracing study in marmoset monkeys. Cerebral Cortex 23(8):1901-22. doi:10.1093/cercor/bhs177 (2013).
David H. Reser, Randika Wijesekara Witharanage, Marcello G.P. Rosa, and Adrian G. Dyer. Honeybees (Apis mellifera) learn color discriminations via differential conditioning independent of long wavelength (green) photoreceptor modulation. PLoS One 7(11): e48577. doi:10.1371/journal.pone.0048577 (2012).
Beltran MA, Paganin DM, Siu KK, Fouras A, Hooper SB, Reser DH, Kitchen MJ. Interface-specific x-ray phase retrieval tomography of complex biological organs. Physics in Medicine and Biology 56(23):7353-69 (2011).
Burman KJ, Reser DH, Richardson KE, Gaulke H, Worthy KH, Rosa MG. Subcortical projections to the frontal pole in the marmoset monkey. European Journal of Neuroscience 34(2):303-19 (2011)
Dyer AG, Paulk AC, Reser DH. Colour processing in complex environments: insights from the visual system of bees. Proceedings of the Royal Society B 278(1707):952-9. (2011)
Kathleen Burman, David Reser, Hsin-Hao Yu, Marcello Rosa. Cortical input to the frontal pole of the marmoset monkey. Cerebral Cortex 21(8):1712-37 (2011)
Hsin-Hao Yu, Richa Verma, Yin Yang, Heath A. Tibballs, Leo L. Lui, David H. Reser and Marcello G.P. Rosa. Spatial and temporal frequency tuning in striate cortex: functional uniformity and specializations related to receptive field eccentricity. European Journal of Neuroscience 31:1043-1062 (2010).
Rosa MG, Palmer SM, Gamberini M, Burman KJ, Yu HH, Reser DH, Bourne JA, Tweedale R, Galletti C. Connections of the dorsomedial visual area: pathways for early integration of dorsal and ventral streams in extrastriate cortex. Journal of Neuroscience 29(14):4548-4563 (2009).
David H. Reser, Kathleen J. Burman , Karyn E. Richardson, Matthew W. Spitzer, and Marcello G.P. Rosa. Connections of the marmoset rostrotemporal auditory area: express pathways for analysis of affective content in hearing. European Journal of Neuroscience 30(4):578-592 (2009).
Dyer AG, Rosa MGP, Reser DH. Honeybees can recognise images of complex natural scenes for use as potential landmarks. Journal of Experimental Biology 211(8):1180-1186 (2008).
Williams SK, Reser DH, Dyer AG. A biologically inspired mechano-optical imaging system based in insect vision. Journal of Biocommunication 34(1):E3-E7 (2008).
Tian B, Reser D, Durham A, Kustov A, Rauschecker JP. Functional specialization in rhesus monkey auditory cortex. Science 292(5515):290-3 (2001).
Fishman YI, Reser DH, Arezzo JC, Steinschneider M. Neural correlates of auditory stream segregation in primary auditory cortex of the awake monkey. Hearing Research 151(1-2):167-187 (2001).
Fishman YI, Reser DH, Arezzo JC, Steinschneider M. Complex tone processing in primary auditory cortex of the awake monkey. II. Pitch versus critical band representation. Journal of the Acoustical Society of America. 108(1):247-62 (2000).
Fishman YI, Reser DH, Arezzo JC, Steinschneider M. Complex tone processing in primary auditory cortex of the awake monkey. I. Neural ensemble correlates of roughness. Journal of the Acoustical Society of America 108(1):235-46 (2000).
Reser DH, Fishman YI, Arezzo JC, Steinschneider M. Binaural interactions in primary auditory cortex of the awake macaque. Cerebral Cortex 10(6):574-84 (2000).
Reser D, Rho M, Dewan D, Herbst L, Li G, Stupak H, Zur K, Romaine J, Frenz D, Goldbloom L, Kopke R, Arezzo J, Van De Water T. L- and D- methionine provide equivalent long term protection against CDDP-induced ototoxicity in vivo, with partial in vitro and in vivo retention of antineoplastic activity. NeuroToxicology 20(5):731-48 (1999).
Fishman YI, Reser DH, Arezzo JC, Steinschneider M. Pitch vs. spectral encoding of harmonic complex tones in primary auditory cortex of the awake monkey. Brain Research 786(1-2):18-30 (1998).
Reser DH, Van de Water TR. Implications of neurotrophin supported auditory neuron survival for maintenance of the tonotopic organization of the central auditory pathway. Acta Otolaryngologica Stockholm 117(2):239-43 (1997).
Steinschneider M, Reser D, Schroeder CE, Arezzo JC. Tonotopic organization of responses reflecting stop consonant place of articulation in primary auditory cortex (A1) of the monkey. Brain Research 674(1):147-52 (1995).