Pregnancy & Fetal Health Laboratory

Publications

2005

Manuepillai, U., Ligam, P., Smythe, G.A., Wallace, E. M., Phillips, D., Guilemin G. J., Hirst, J.J., Brew, B., Walker, D.W. 2005  Infection in pregnancy: Potential contribution of placental tryptophan metabolites to perinatal brain damage. Am J Obstet Gynecol 192:280-288.

Palliser, H.K., Hirst, J.J., Ooi, G.T., Rice, G.E., Escalona, R.M., Dellios, N.L., Parkington, HC., Young, I.R. 2005 Prostaglandin E and F receptor expression and myometrial sensitivity at labour onset in sheep. Biol Reprod. 72:937-943

Hirst, J. J.  Parkington, H. C., Young, I.R.,  Palliser, H.K., Peri, K.G., Olson, D. M. 2005  Delay of preterm birth by THG113.31, a  prostaglandin F_2a receptor antagonist. Am J Obstet Gynecol 192: (In press Oct 2004) .

Castillo-Melendez M, Yan E, Walker DW 2005 Expression of EPO and its receptor in the late gestation fetal sheep brain following umbilical cord occlusion. Dev Neurosci. (in press Nov 2004).

Dickinson H, Walker DW, Cullen-McEwan L, Wintour M, Moritz K (2005) Spiny mouse (Acomys caharinus) completes nephrogenesis prior to birth. Am J. Physiology (accepted Jan. 2005).

2004

Yan, E., Castillo-Melendez, M., Nicholls, T., Hirst, J.J., & Walker, D.W. (2004) Cerebrovascular responses in the fetal brain to low dose endotoxin. Pediatr. Res. 55: 855-863.

Castillo-Melendez, M., Chow, J-A., Walker, D.W. (2004) Lipid peroxidation, caspase-3 immunmoreactivity, and pyknosis in late gestation fetal sheep brain after umbilical cord occlusion. Pediatr. Res. 55:864-871.

Manuelpillai U, Ligam P, Smythe GA, Wallace EM, Walker DW. (2004)  Identification of kynurenine pathway enzyme mRNAs and metabolites in human placenta: up-regulation by inflammatory stimuli and with clinical infection. Am. J. Obstet. Gynecol. 192: 280-288.

Ligam P, Manuelpillai U, Wallace EM, Walker DW (2004) Localization of indoleamine 2,3-dioxygenase and kynurenine hydroxylase in the human placenta and decidua: implications for the role of the kynurenine pathway in pregnancy.  Placenta  (in press Nov 2004).

Palliser, H.K., Dellios, N., Escalona, R., Ooi, G., Rice, G.E., Hirst, J.J., Young, I.R. 2004 prostaglandin synthetic enzymes in the ovine myometrium, endometrium and placenta during induced-preterm and spontaneous. J. Endocrinol 180: 469-477

Nguyen, P. N., Young, I.R., Walker, D. W., Hirst, J.J.  2004 Neurosteroids in the brain and blood after disruption of the hypothalamo –pituitary-adrenal axis in fetal sheep. J Endocrinal. 182: 81-88.

Nguyen, P. N., Yan, E. B., Castillo-melendez, M., Walker, D. W., Hirst, J. J. 2004 Increased allopregnanolone concentrations in the fetal brain following umbilical cord occlusion. J. Physiol.  560 Part 2: 593-602