The mechanism of thymic stromal directed T-cell differentiation has been a keen interest since the early 90's. I have also played a role in the search to define a thymic stem cell population. In recent years my position of Lab Manager has led me to other projects including one to enable our research scientists to perform and capture their research data more efficiently. To this end I have used an acquired knowledge of information technology to conceive an in-house electronic notebook and in conjuction with ARMI, MeRC (Monash e-Research Centre) and the Faculty of Medicine continue to develop this software.
Uldrich, A.P., Berzins, S.P., Malin, M.A., Bouillet, P., Strasser, A., Smyth, M.J., Boyd, R.L.* and Godfrey, D.I.* (2006). Antigen challenge inhibits thymic emigration. J. Immunol. 176: 4553-4561 (* equal contribution)
Sutherland, J.S., Goldberg, G.L., Hammett, M.V., Uldrich,, A.P., Berzins, S.P.,Heng, T.S., Blazar, B.R., Millar, J.L., Malin, M.A., Chidgey, A.P., and Boyd, R.L. (2005). Activation of thymic regeneration in mice and humans following androgen blockade. Journal of Immunology, 175(4):2741-53
Gray DH, Ueno T, Chidgey AP, Malin M, Goldberg GL, Takahama Y, Boyd RL. Controlling the thymic microenvironment. Curr Opin Immunol. 2005 Apr;17(2):137-43.
Gill J, Malin M, Sutherland J, Gray D, Hollander G, Boyd R. Thymic generation and regeneration. Immunol Rev. 2003 Oct;195:28-50. Review.
Flentjar NJ, Crack PJ, Boyd R, Malin M, de Haan JB, Hertzog P, Kola I, Iannello R. Mice lacking glutathione peroxidase-1 activity show increased TUNEL staining and an accelerated inflammatory response in brain following a cold-induced injury. Exp Neurol. 2002 Sep;177(1):9-20.
Gill, J., Malin, M., Holländer, G.A., and Boyd, R.L. (2002). Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells. Nature Immunology 2002 3 (7): 635-42
Ueno T, Hara K, Willis MS, Malin MA, Hopken UE, Gray DH, Matsushima K, Lipp M, Springer TA, Boyd RL, Yoshie O, Takahama Y. Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity 2002 16: 205-218
Berzins SP, Davey GM, Randle-Barrett ES, Malin MA, Classon BJ, Fraser S, Boyd RL. Thymic shared antigen-2: a novel cell surface marker associated with T cell differentiation and activation. J Immunol. 1999 May 1;162(9):5119-26
Williams GS, Malin M, Vremec D, Chang CH, Boyd R, Benoist C, Mathis D. Mice lacking the transcription factor CIITA--a second look. Int Immunol. 1998 Dec;10(12):1957-67.
Blackburn CC, Augustine CL, Li R, Harvey RP, Malin MA, Boyd RL, Miller JF, Morahan G. The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5742-6.
Godfrey DI, Masciantonio M, Tucek CL, Malin MA, Boyd RL, Hugo P. Thymic shared antigen-1. A novel thymocyte marker discriminating immature from mature thymocyte subsets. J Immunol. 1992 Apr 1;148(7):2006-11.
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