List of publications on Shigella

Sakellaris H, Luck SN, Al-Hasani K, Rajakumar K, Turner S, Adler B. (2004) Regulated site-specific recombination of the she pathogenicity island of Shigella flexneri. Mol. Microbiol. 52, 1329-1336.

Turner SA, Luck SN, Sakellaris H, Rajakumar K, Adler B. (2004) Role of attP in integrase-mediated integration of the SRL pathogenicity island of Shigella flexneri. Antimicrob. Ag. Chemother. 48, 1028-1031.

Turner S, Luck S, Sakellaris H, Rajakumar K, Adler B. (2003) Molecular epidemiology of the SRL pathogenicity island. Antimicrob. Ag. Chemother. 47, 727-734. 

Luck S, Turner S, Rajakumar K, Sakellaris H, Adler B. (2001) Ferric dicitrate transport system (Fec) of Shigella flexneri 2a YSH6000 is encoded on a novel pathogenicity island encoding antibiotic resistance. Infect. Immun.,  69, 6012-6021. 

Turner S, Luck S, Sakellaris H, Rajakumar K, Adler B. (2001) Nested deletions of the SRL pathogenicity island of Shigella flexneri 2a. J. Bacteriol., 183, 5535-5543. 

Al-Hasani K, Adler B, Rajakumar K, Sakellaris H. (2001)  Distribution and structural variation of the she pathogenicity island in enteric bacterial pathogens. J. Med. Microbiol., 50, 780-786. 

Al-Hasani K, Rajakumar K, Robins-Browne RM, Adler B, Sakellaris H. (2001)  Genetic organisation of the she pathogenicity island in Shigella flexneri 2a. Microb. Pathog., 30, 1-8. 

Al-Hasani K, Henderson I, Sakellaris H, , Grant T, Nataro J, Robins-Browne RM, Rajakumar K Adler B. (2000) The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation. Infect Immun., 68, 2457-2463. 

Sakellaris H, Rajakumar K, Hannink N, Hunt ML, Sasakawa C, Adler B. (2000)   Curli loci of Shigella spp. Infect. Immun., 68, 3780-3783. 

Rajakumar K, Sasakawa C, Adler B (1997) Use of a novel approach termed 'island probing' identifies the Shigella she pathogenicity island which encodes a homologue of the IgA protease-like family of proteins. Infect. Immun. 65, 4606-4614. 

Rajakumar K, Bulach D, Davies JK, Ambrose L, Sasakawa C, Adler B (1997) Identification of a chromosomal Shigella flexneri multi-antibiotic resistance locus which shares sequence and organisational similarity with the resistance region of the plasmid NR1. Plasmid. 37, 159-168. 

Rajakumar K, Luo F, Sasakawa C, Adler B (1996) Evolutionary perspective on a composite Shigella flexneri 2a virulence plasmid-borne locus comprising three distinct genetic elements. FEMS Microbiol. Lett. 144, 13-20. 

Rajakumar K, Sasakawa C, Adler B (1996) A spontaneous 99 kb chromosomal deletion results in multi-antibiotic sensitivity and an atteunation of contact haemolysis in Shigella flexneri 2a. J. Med. Microbiol. 45, 64-75. 

Rajakumar K, Jost BH, Sasakawa C, Okada N, Yoshikawa M, Adler B (1994) Nucleotide sequence of the rhamnose biosynthetic operon of Shigella flexneri 2a and role of LPS in virulence. J. Bacteriol., 176, 2362-2373. 

Jost BH, Adler B (1993) Site of activation of virB on the large plasmid of Shigella flexneri by VirF, a member of the AraC family of transcriptional activators. Microb. Pathogen. 14, 481-488. 

Sasakawa C, Tobe T, Nagai S, Okada N, Adler B, Komatsu K, Yoshikawa M. (1991) Thermoregulation of invasion genes in Shigella flexneri through the transcriptional activation of the virB gene on the large plasmid. In, Molecular Pathogenesis of Gastro-Intestinal Infections. (Wadstrom T et al., Eds.), pp.217-221. Plenum Press. New York. 

Tobe T, Nagai S, Okada N, Adler B, Yoshikawa M, Sasakawa C (1991) Temperature-dependent expresion of invasion genes in Shigella flexneri is controlled through the transcriptional activation of the virB gene on the large plasmid. Mol. Microbiol., 5, 887-893. 

Sasakawa C, Adler B, Tobe T, Okada N, Nagai S, Komatsu K, Yoshikawa M (1989) Functional organization and nucleotide sequence of virulence Region-2 on the large plasmid in Shigella flexneri 2a. Mol. Microbiol., 3, 1191-1202. 

Adler B, Sasakawa C, Tobe T, Makino S, Komatsu K, Yoshikawa M (1989) A dual transcriptional activation system for the 230 kb plasmid genes coding for virulence-associated antigens of Shigella flexneri. Mol. Microbiol., 3, 627-635.

PhD theses

Rajakumar K. (1995) Characterisation of chromosomal virulence-associated loci of Shigella flexneri 2a

Al-Hasani K. (2001) Characterisation of the she pathogenicity island of Shigella flexneri2a

Luck S. (2003) The SRL pathogenicity island of Shigella flexneri2a YSH6000

Turner S. (2003) Genetics of the SRL pathogenicity island of Shigella