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Dr Richard Beare

Dr Richard BeareDr Beare is a Senior Research Fellow in Imaging within the Department of Medicine at Monash Medical Centre (Monash University). He conducts and supervises computational image analysis within the Stroke and Ageing Research Group.
He has developed new image analysis methods for two large human brain studies (TASCOG, CDOT). He has particular expertise in semi-automated segmentation of white matter hyperintensities, structural analysis using voxel-based morphometry, spherical harmonic based shape analysis of brain structures and multivariate image analysis. Involvement in the Australian Mouse Brain Mapping Consortium has led Dr Beare to develop new tools for structural analysis and computational anatomy of animal models. A further interest is the development of imaging techniques for measuring vascular geometry and flow modeling.
As well as contributing to the Insight Toolkit, the internationally recognised, NIH funded software suite for medical image analysis, Dr Beare holds 4 patents, has contributed to a number of commercial software packages (Axon ImageXpress, Evotech high content screening platform) and products (Enterix bowel cancer screening, robotic equipment) while working for CSIRO.

 

Morphological segmantation of age-related white matter lesions

 

Current Research
Tasmanian study of cognition and gait (TASCOG) - a large, population based study of healthy aged subjects examining the relationships between brain structure and gait and cognitive function. 400 subjects are being studied longitudinally.

  • Australian Mouse Brain Mapping Consortium - construction of the next generation of mouse brain atlas. This will be a probabalistic atlas and is being built using high resolution MRI and microscopy imagery.
  • Carotid artery segmentation and modelling for improved stroke risk estimation.
  • Fatigue, depression and traumatic brain injury. This study is attempting to correlate damage resulting from traumatic brain injury to sleep and psychological disorders. My role is to develop the procedures to make automated measurements from the brain scans and carry out the statistical analysis.
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Research Interests

  • Image analysis for large studies of abnormal subjects.
  • Exploratory analysis methods for neuroimaging.
  • Computational anatomy.
  • Segmentation methods.
  • Multiple object tracking, matching and registration. Application areas include matching of 2D gels and tracking platelets.
  • Coupled tracking and segmentation.
  • Region based segmentation methods.
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Major Collaborations

  • Monash-CSIRO Collaborative Research in Carotid Flow Modelling
  • The Australian Mouse Brain Mapping Consortium (involving Monash University, Queensland Brain Institute (University of Queensland), University of New South Wales (POWMRI))
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PhD Thesis

“Image segmentation based on local motion detection”.Department of Electrical and Electronic Engineering, University of Adelaide, 1998.

Journal Publications

  • Beare R, Srikanth V, Phan TG, Chen J, Stapleton J, Lipshut R, Reutens DC. Morphological segmentation of white matter hyperintensities. Neuroimage (accepted March 19, 2009).
  • V. Srikanth, R. Beare, J. Chen, J. Stapleton, T. Phan, and D. Reutens. Cerebral white matter lesions, gait and the risk of incident falls a prospective population-based study. Stroke, 40(1):175–180, January 2009.
  • C. Sun, R. Beare, K. Cheong, B.J. Jung, and M. Kim. Stereoscopic Flatbed scanner. Journal of Electronic Imaging, 2009.
  • Y. Glickmann-Johnston, M. Saling, J. Chen, K. Cooper, R. Beare, and D. Reutens. Structural and functional correlates of unilateral mesial temporal lobe spatial memory impairment. Brain. 2008 Nov;131(Pt 11):3006-18.
  • R. Beare, K. Richards, S. Petrou, and D. Reutens. An assessment of methods for aligning two dimensional microscope sections to create image volumes. Journal of Neuroscience Methods, 170(2):332–344, 2008.
  • M. Berman, R. Beare, D. Coward, L. Whitbourn, C. Evans, Osborne. B., P. Connor, R. Phillips, and R. Quodling. Measurement of wheat grain thickness using profilometry. Cereal Chemistry, 84(3):282–284, 2007.
  • C. Sun, R. Beare, V. Hilsenstein, and P. Jackway. Mosaicking of microscope images with global geometric and radiometric corrections. Journal of Microscopy, 224:158–165, November 2006.
  • R. Beare. A locally constrained watershed transform. IEEE Transactions on Pattern Analysis and Machine Intelligence, 28(7):1063–1074, July 2006.
  • Sun, R. Jones, H. Talbot, X. Wu, K. Cheong, R. Beare, M. Buckley, and M. Berman. Measuring the distance of vegetation from powerlines using stereo vision. ISPRS Journal of Photogrammetry and Remote Sensing, 60(4):269–283, June 2006

Open Access Publications

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List of Grants for 2002-2009

  • 2006: Grant Type – ARC Linkage, Equipment, Infrastructure, Facilities for $160,000. Project – Distributed Medical Image Analysis and Visualisation Engine (MedVis). Investigators: Prof H Schmidt, Dr R Beare.
  • 2007: Grant Type – Monash-CSIRO Collaborative Research Support Scheme for $43,500. Project – Geometric Model Creation for blood flow simulation. Investigators – Beare, Phan, Srikanth, Sinnott.
  • 2008: Grant Type - Victorial Partnership for Advanced Computing, e-Research Program Grant Scheme for $18,500. Project – Flexible annotated medical image data store. Investigator – Beare.
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Stroke and Ageing Research