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Associate Professor Jennifer Wilkinson-BerkaCurrent Position: Phone: Facsimile: Email: Office: Laboratory: Profile: Current Research Focus: Selected Publications: Wilkinson-Berka JL, Tan G, Jaworski K, Ninkovic S. Valsartan but not Atenolol Improves Vascular Pathology in Diabetic Ren-2 Rat Retina. Am J Hypertens. 2007;20(4):423-30. Phipps JA, Wilkinson-Berka JL, Fletcher EL. Retinal dysfunction in diabetic ren-2 rats is ameliorated by treatment with valsartan but not atenolol. Invest Ophthalmol Vis Sci. 2007;48(2):927-34. Wilkinson-Berka JL, Wraight C, Werther G. The role of growth hormone, insulin-like growth factor and somatostatin in diabetic retinopathy. Curr Med Chem. 2006;13(27):3307-17. Review. Wilkinson-Berka JL, Jones D, Taylor G, Jaworski K, Kelly DJ, Ludbrook SB, Willette RN, Kumar S, Gilbert RE. SB-267268, a nonpeptidic antagonist of alpha(v)beta3 and alpha(v)beta5 integrins, reduces angiogenesis and VEGF expression in a mouse model of retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1600-5. Wilkinson-Berka JL. Angiotensin and diabetic retinopathy. Int J Biochem Cell Biol. 2006;38(5-6):752-65. Epub 2005 Sep 1. Review. Fletcher EL, Phipps JA, Wilkinson-Berka JL. Dysfunction of retinal neurons and glia during diabetes. Clin Exp Optom. 2005 May;88(3):132-45. Review. Sarlos S, Wilkinson-Berka JL. The renin-angiotensin system and the developing retinal vasculature. Invest Ophthalmol Vis Sci. 2005 Mar;46(3):1069-77. Wilkinson-Berka JL, Babic S, De Gooyer TE, Stitt AW, Jaworski K, Ong GT, Kelly DJ, Gilbert RE. Inhibition of platelet derived growth factor promotes pericyte loss and angiogenesis in ischaemic retinopathy. Am J Pathol. 2004;164:1263-1273 Wilkinson-Berka JL, Fletcher EL. Angiotensin and bradykinin: targets for the treatment of vascular and neuro-glial pathology in diabetic retinopathy. Curr Pharm Des. 2004;10:3313-3330 Wilkinson-Berka JL. Diabetes and retinal vascular disorders: role of the reninangiotensin system. Expert Rev Mol Med. 2004 Jul 23;6(15):1-18. Sarlos S, Rizkalla B, Moravski CJ, Cao Z, Cooper ME, Wilkinson-Berka JL. Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietin. Am J Pathol. 2003;163:879-887 Moravski CJ, Skinner SL, Stubbs AJ, Sarlos S, Kelly DJ, Cooper ME, Gilbert RE, Wilkinson-Berka JL. The renin-angiotensin system influences ocular endothelial cell proliferation in diabetes: transgenic and interventional studies. Am J Pathol. 2003;162:151-160 Wilkinson-Berka JL, Kelly SJ, Koerner SM, Jaworski K, Davis B, Thallas V, Cooper ME. ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat. Diabetes. 2002;51:3283-289
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