Hyperbaric Oxygen in Lower Limb Trauma (HOLLT)
HOLLT is an international multi-centre randomised clinical trial aimed at assessing the impact of hyperbaric oxygen therapy (HBO) on acute complication rates and long term outcomes following severe musculoskeletal trauma.
The study will enrol 250 patients with severe, open tibial fractures over a 2-3 year period. Eligible patients will be randomised to either receive 12 sessions of HBO or to not receive HBO during the acute phase of care. Enrolled subjects will be followed up for 2 years with radiological, clinical and quality of life measures.
Chief Investigators
Dr Ian Millar, The Alfred Hyperbaric Service
Prof Peter Cameron, Monash University
Prof Owen Williamson, Monash University
Prof Paul Myles, The Alfred Hospital
Project Coordinator
Ms Rosemary Mc Ginnes, Project Coordinator
Department Epidemiology and Preventive Medicine
Monash University
Alfred Hospital
Commercial Road
Melbourne, VIC, 3004
Australia
Tel +61 (0)3 9903 0926
Fax +61 (0)3 9903 0576
Email: hollt@med.monash.edu.au
HOLLT Web Database
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