Role of the Microcirculation in the Development of Cognitive Impairment: A sub-study of the Cognition and Type 2 Diabetes in Older Tasmanians Study (CDOT)

Project Team

• R Tapp (Monash University, Chief Investigator A)
• V Srikanth (Monash University)
• A Venn (Menzies Research Institute)
• C Magnussen (Menzies Research Institute)
• N Chaturvedi (Imperial College London)
• S Thom (Imperial College London)
• A Hughes (Imperial College London)
• N Witt (Imperial College London)

Project Outline

This project funded by a support grant from Monash University will investigate the association between the microcirculation and cognitive decline. It is increasingly recognised that microcirculatory dysfunction is critical to our understanding of the mechanisms linking diabetes to later cognitive decline. Retinal examination offers an ideal opportunity to study the microcirculation in a non-invasive fashion to further our understanding of disease pathogenesis. The project is a sub-study of the CDOT designed to examine the cross-sectional associations between brain structure and cognitive decline