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Impact of Size at Birth and Early Childhood Growth Patterns on the Microvasculature: the Avon Longitudinal Study of Parents and Children (ALSPAC sub-study)
Project Team
Project Outline
This project funded by the British Heart Foundation will investigate the impact of low birth weight and postnatal growth patterns on the microvasculature of the retina in a birth cohort of children followed over the first 12 years of life. In collaboration with the Imperial College London and Bristol University we have undertaken measurements of retinal microvascular abnormalities using digitally acquired retinal images analysed by an extensively validated semi-automated analysis system.
Project Outcomes
The results of this study will provide novel insight into possible mechanisms linking early life events with future risk of hypertension, cardiovascular disease and diabetes and may contribute to development of appropriate early treatment and intervention.
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