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Immunity
Here we aim to provide a fundamental advancement of knowledge of events that are central to innate and adaptive immunity. Understanding the structural and biophysical basis of MHC-restriction, TCR engagement, the structural correlates of T-cell signalling is significant; they represent central questions in the field of adaptive immunity. Moreover, investigating the structural basis of T-cell allorecognition, and T-cell mediated autoimmunity, will collectively provide clear insights into immune dysfunction. In addition, focussing on generic components of innate immunity is important, as the mechanisms underlying innate recognition, is simply unknown.
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Project Team
- Travis Beddoe,
- Craig Clements,
- Hugh Reid,
- Whitney Macdonald,
- Natalie Borg,
- Fleur Tynan,
- Julia Archbold,
- Hilary Hoare,
- Kate Henderson,
- Kwok Wun
- Stephanie Gras
- Ray Koh
- Emma Hopkins
- Yu Chih Liu
- Kent Cheng
- Li Zeng
- Sophie Broughton
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