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Michelle Dunstone's Publications

Refereed Primary Publications

  • C.J. Rosado, A.M. Buckle, R.H.P. Law, R.E. Butcher, W. Kan, C.H. Bird, K. Ung, K.A. Browne, K. Baran, T.A. Bashtannyk-Puhalovich, N.G. Faux, W. Wong, C.J. Porter, R.N. Pike, A.M. Ellisdon, M.C. Pearce, S.P. Bottomley, J. Emsley, A.I. Smith, J. Rossjohn, E.L. Hartland, I. Voskoboini, J.A. Trapani, P.I. Bird, M.A. Dunstone$ and J.C. Whisstock$ “A common fold mediates vertebrate defense and bacterial attack.” Science 317(5844):1548-51 (2007).$ Joint senior and corresponding author.   Impact Factor: 30.0   Time Cited: 4
  • F.M. Sansom, P. Riedmaier, H.J. Newton, M.A. Dunstone, C.E. Müller, H. Stephan, E. Byres, T. Beddoe, J. Rossjohn, P.J. Cowan, A.J. d'Apice, S.C. Robson, E.L. Hartland. “Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.” Journal of Biological Chemistry 283(19) 12909-18 (2008).   Impact Factor: 5.8   Time Cited: 0
  • N.S. Butler, A. Theodossis, A.I. Webb, M.A. Dunstone, R. Nastovska, S.H. Ramarathinam, J. Rossjohn, A.W. Purcell and S. Perlman. “Structural and biological basis of CTL escape in coronavirus-infected mice.” Journal of Immunology 180(6):3926-37 (2008).   Impact Factor: 6.3   Time Cited: 0
  • N.L. La Gruta, P.G. Thomas, A.I. Webb, M.A. Dunstone, T. Cukalac, P.C. Doherty, A.W. Purcell, J. Rossjohn and S.J. Turner. “Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides.” Proceedings of the National Academy of Sciences USA. 105(6):2034-9 (2008).   Impact Factor: 9.6   Time Cited: 0
  • A.I. Webb, M.A. Dunstone, N.A. Williamson, J.D. Price, A. de Kauwe, W.S. Chen, A. Oakley, P. Perlmutter, J. McCluskey, M.I. Aguilar, J. Rossjohn and A.W. Purcell. “T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo.” Journal of Immunology 175(6) 3810-8 (2005).   Impact Factor: 6.3   Time Cited: 7
  • S.J. Turner, K. Kedzierska, H. Komodromou, N.L. La Gruta, M.A. Dunstone, A.I. Webb, R. Webby, H. Walden, W. Xie, J. McCluskey, A.W. Purcell, J. Rossjohn and P.C. Doherty. “Lack of prominent peptide-MHC features limits T cell receptor repertoire diversity in virus-specific CD8+ T populations.” Nature Immunology 6(4) 382-9 (2005).   Impact Factor: 27.6   Time Cited: 43
  • C.S. Clements, L. Kjer-Nielsen, L. Kostenko, H.L. Hoare, M.A. Dunstone, E. Moses, K. Freed, A.G. Brooks, J. Rossjohn and J. McCluskey. “Crystal structure of HLA-G: A nonclassical MHC class 1 molecule expressed at the fetal-maternal interface.” Proceedings of the National Academy of Sciences USA. 102(9) 3605 (2005).   Impact Factor: 9.6   Time Cited: 28
  • M.A. Dunstone†, L. Kjer-Nielsen†, L. Kostenko, A.W. Purcell, A.G. Brooks, J. Rossjohn and J. McCluskey. "The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody." Acta Crystallographica Section D-Biological Crystallography 60(Pt 8) 1425-8 (2004).† Joint first author.   Impact Factor: 1.7   Time Cited: 1
  • A.I. Webb, N.A. Borg, M.A. Dunstone, L. Kjer-Nielsen, T.C. Beddoe, J. McCluskey, F.R. Carbone, S.P. Bottomley, M.I. Aguilar, A.W. Purcell and J. Rossjohn. "The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance." Journal of Immunology 173(1) 402-9 (2004).   Impact Factor: 6.3   Time Cited: 16
  • L. Kjer-Nielsen†, M.A. Dunstone†, L. Kostenko, L.K. Ely, T. Beddoe, N.A. Mifsud, A.W. Purcell, A.G. Brooks, J. McCluskey and J. Rossjohn. “Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.” Proceedings of the National Academy of Sciences USA. 101(20) 7675-80 (2004). † Joint first author.   Impact Factor: 9.6   Time Cited: 24
  • A.I. Webb†, M.A. Dunstone†, W. Chen, M.I. Aguilar, Q. Chen, H. Jackson, L. Chang, L. Kjer-Nielsen, T. Beddoe, J. McCluskey, J. Rossjohn and A.W. Purcell. "Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue." Journal of Biological Chemistry 279(22) 23438-46 (2004). † Joint first author.   Impact Factor: 5.8   Time Cited: 12
  • M.A. Dunstone†, W. Dai†, J.C. Whisstock, J. Rossjohn, R.N. Pike, S. Feil, B.F. Le Bonniec, M.W. Parker, S.P. Bottomley. “Cleaved Antitrypsin Polymers at Atomic Resolution.” Protein Science  9: 1-4 (2000). † Joint first author.   Impact Factor: 3.5   Time Cited: 39

Invited / Refereed Reviews

  • C.J. Rosado, S. Kondos, T.E. Bull, M.J. Kuiper, R.H.P. Law, A.M. Buckle, I. Voskoboinik, P.I. Bird, J.A.Trapani, J.C. Whisstock and M.A. Dunstone “The MACPF / CDC family of pore forming toxins.” Cellular Microbiology (In press, 2008). $ Joint senior and corresponding author.  Impact Factor: 5.1   Time Cited: 0
  • C.S. Clements†, M.A. Dunstone†, W.A. Macdonald, J. McCluskey and J. Rossjohn. “Specificity on a knife-edge: the alphabeta T cell receptor.” Current Opinion in Structural Biology 16(6) 787-95 (2006). † Joint first author.  Impact Factor: 11.2   Time Cited: 10